Endpoint Security Best Practices

Comprehensive strategies to secure your organization's endpoints and eliminate security blind spots

The Critical Importance of Endpoint Security

In today's threat landscape, endpoints have become the primary battleground for cybersecurity. Recent data reveals that 90% of successful cyberattacks and 70% of data breaches originate at endpoint devices, while the global average cost of a data breach reached $4.88 million in 2024 - a 10% increase from the previous year.

With 72.7% of organizations worldwide falling victim to ransomware attacks in 2023, comprehensive endpoint security strategies are no longer optional but essential for protecting your organization's valuable data and maintaining operational continuity.

Essential Endpoint Security Best Practices

Maintain Endpoint Inventory

Maintain comprehensive visibility of all endpoints connected to your network. Deploy automated tools and conduct routine audits to identify unauthorized or vulnerable endpoints, ensuring compliance with industry standards.

Robust Security Protection

Deploy comprehensive endpoint security solutions with real-time malware detection, regular updates, and behavior-based threat detection capabilities to defend against sophisticated attacks including ransomware.

Proactive Vulnerability Management

Implement automated vulnerability scanning and patch management systems. With over 6 million data records exposed in Q1 2023 alone, timely patching is critical to prevent endpoints from becoming easy targets.

Access Controls & Encryption

Implement strong access controls with multi-factor authentication, principle of least privilege, and full-disk encryption. Enable firewalls and use application whitelisting to prevent unauthorized software execution.

Monitoring & Incident Response

Deploy centralized logging and monitoring tools to track endpoint activities. Develop comprehensive incident response plans and conduct regular security assessments to identify and address vulnerabilities.

User Education & Training

Provide regular security awareness training to employees about common threats, phishing attacks, and secure data handling practices. Foster a security-conscious culture throughout the organization.

Microsoft Intune Endpoint Security Management

Microsoft Intune's Endpoint Security node provides comprehensive tools for managing device security and mitigating risks across your organization's endpoints with integrated cloud-native protection.

Unified Management

Cross-platform device management for Windows, iOS, Android, and macOS from a single console.

Security Baselines

Deploy and manage security baselines with focused policies for antivirus, encryption, and firewalls.

Threat Detection

Automated threat detection and response with Microsoft Defender for Endpoint integration.

Key Capabilities

Device Compliance Monitoring

Comprehensive monitoring and reporting of device compliance across all platforms.

Security Baseline Management

Deployment and management of security baselines for consistent protection.

Focused Security Policies

Granular policies for antivirus, encryption, firewall, and endpoint protection.

Microsoft Defender Integration

Seamless integration with Microsoft Defender for Endpoint for advanced protection.

Advanced Security Features

Conditional Access Policy Enforcement

Enforce access policies based on device compliance and user context.

Security Task Management

Automated security task management and remediation workflows.

Cross-Platform Management

Unified management across Windows, iOS, Android, and macOS devices.

Automated Threat Response

Real-time threat detection with automated response and remediation.

Cloud-Native Security

Leverages Microsoft's cloud infrastructure for scalable endpoint protection.

Omnissa Security and Compliance

Omnissa's security and compliance platform creates a self-securing environment with continuous posture verification, helping organizations manage complexity, streamline security, minimize attack surfaces, and maximize user productivity.

Safeguard Apps

Protect any app with granular policies, SSO, MFA, and application tunneling across networks, users, and data.

Remediate Rapidly

Respond to vulnerabilities and threats efficiently through templated workflows in UEM and ecosystem integration.

Maximize Investment

Unite teams and technologies with AI-powered insights, workflow orchestration, and cross-platform integration.

Core Use Cases

Validate Access

Enable productivity with conditional access by connecting posture, risk assessment, and entitlements to application access decisions.

Mitigate Threats

Leverage UEM and third-party information to protect against phishing, application, and rogue network threats.

Automate Compliance

Proactively enforce endpoints to a desired state and prioritize vulnerability remediation via templated workflows.

Analyze & Orchestrate

Evaluate access and endpoint risk using machine learning to proactively surface and fix problems.

Security-First Products

Workspace ONE UEM

Deliver and manage any app, on any device, anywhere with comprehensive security controls.

Omnissa Access

Integrate with leading identity providers to optimize secure application access.

Mobile Threat Defense

Protect against phishing, device vulnerabilities, and advanced mobile threats.

Workspace ONE Tunnel

Achieve zero trust goals with secure VPN and application tunneling capabilities.

Omnissa Intelligence

Get real-time insights and automated features powered by AI and machine learning.

Endpoint Security by the Numbers

90%

of successful cyberattacks originate at endpoint devices

$4.88M

global average cost of a data breach in 2024

72.7%

of organizations fell victim to ransomware attacks in 2023

Secure Your Endpoints Today

Ready to implement comprehensive endpoint security? Let's discuss your security requirements and develop a tailored solution.

Sources

1. Cybersecurity News. (2023). "Securing Endpoints: 6 Best Practices to Eliminate Blind Spots."https://cybersecuritynews.com/endpoint-security-best-practices/

2. Microsoft Learn. (2025). "Manage endpoint security in Microsoft Intune."https://learn.microsoft.com/en-us/intune/intune-service/protect/endpoint-security

3. SentinelOne. (2024). "Cybersecurity Statistics."https://www.sentinelone.com/cybersecurity-101/cybersecurity/cyber-security-statistics/

4. Guardz. (2025). "36 Endpoint Security Statistics MSPs Should Know About in 2025."https://guardz.com/blog/36-endpoint-security-statistics-msps-should-know-about-in-2025/

5. Cobalt. (2023). "Top Cybersecurity Statistics."https://www.cobalt.io/blog/top-cybersecurity-statistics-for-2022

6. Omnissa. (2025). "Security & Compliance - Omnissa Platform."https://www.omnissa.com/platform/security-and-compliance/

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